"Heavy firing was also reported, where residents said a thick cloud of smoke had engulfed the Hayatabad's phase V area. While residents said three explosions took place inside the Imamia Masjid Imambargah at the time of Friday prayers, police did not confirm the blast inside the Shia place of worship," Dawn.com reported.
Security and rescue teams were dispatched to the spot.
The area has been cordoned off following the attack.
All hospitals in the area have been put on high alert.